Randomized Clinical Trial of Lactate Clearance Versus Central Venous Oxygen Saturation for the Optimal Endpoint of Early Sepsis Resuscitation (COMPLETED):
Alan E Jones, MD, Study Director, Carolinas Medical Center
The purpose of this study is to determine if there is equivalence between two different methods of treating patients with severe bloodstream infection called sepsis. We will randomly assign patients to one of two treatment methods. One of the treatment methods is the current standard of care and uses an infrared sensor on the end of a catheter to determine the adequacy of treatment. The second treatment method is identical to the first but instead of the infrared sensor a blood test that is performed as a part of standard care (with blood drawn from the catheter) will be used to determine the adequacy of treatment. This study will attempt to determine an easier method of guiding treatment.
ClinicalTrials.gov identifier NCT00372502
Alan E Jones, MD 704-355-7092 alan.jones@carolinas.org